產(chǎn)品編號(hào) | bsm-61204R |
英文名稱 | Androgen receptor Recombinant Rabbit mAb |
中文名稱 | 雄激素受體重組兔單抗 |
別 名 | ANDR; Androgen receptor; DHTR; Dihydrotestosterone receptor; NR3C4; SBMA; SMAX1 HYSP1; AR; AIS; TFM; KD; |
抗體來源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 3e+14 |
交叉反應(yīng) | Human,Mouse,Rat |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 99 kDa |
檢測分子量 | |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human Androgen receptor |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. SWISS: P10275 Gene ID: 367 AR是一個(gè)由917個(gè)氨基酸組成的蛋白質(zhì),位于雄激素靶組織細(xì)胞中或細(xì)胞表面上的特異分子部位或結(jié)構(gòu)。 AR在前列腺癌中起著重要的作用,研究表明AR的表達(dá)與組織分型形成一定的相關(guān)性 ,AR在高分化的腫瘤中表達(dá)較多,而在低分化的腫瘤中表達(dá)較少。用于前列腺癌的檢測,指導(dǎo)臨床治療,目前可用于乳腺癌、食道癌等各項(xiàng)腫瘤的研究。 |
產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with Androgen receptor monoclonal antibody, unconjugated (bsm-61204R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Breast; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Androgen receptor Monoclonal Antibody, Unconjugated(bsm-61204R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023)and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Prostate Tumor; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Androgen receptor Monoclonal Antibody, Unconjugated(bsm-61204R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023)and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Androgen receptor Monoclonal Antibody, Unconjugated(bsm-61204R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023)and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Androgen receptor Monoclonal Antibody, Unconjugated(bsm-61204R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023)and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Androgen receptor Monoclonal Antibody, Unconjugated(bsm-61204R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023)and DAB (C-0010) staining.
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