| 產(chǎn)品編號(hào) | bsm-61221R |
| 英文名稱 | CCR3 Recombinant Rabbit mAb |
| 中文名稱 | 細(xì)胞表面趨化因子受體3重組兔單抗 |
| 別 名 | CCR3; CD193; CCCKR3; CMKBR3; CKR3; CMKBR1L2; C-C chemokine receptor type 3. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 12F9 |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41 kDa |
| 檢測(cè)分子量 | 60 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCR3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. SWISS: P51677 Gene ID: 1232 趨化因子受體3(CCR3)主要在嗜酸粒細(xì)胞，Th2淋巴細(xì)胞，肥大細(xì)胞，支氣管上皮細(xì)胞上表達(dá)， CCR3介導(dǎo)嗜酸粒細(xì)胞內(nèi)有絲分裂原活化蛋白激酶（MAPK） 細(xì)胞外信號(hào)調(diào)節(jié)激酶-2（ERK2）、p38和JNK的活化。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with CCR3 monoclonal antibody, unconjugated (bsm-61221R) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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