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HSP47 Recombinant Rabbit mAb (bsm-61347R)  
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25ul/800.00元
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產(chǎn)品編號(hào) bsm-61347R
英文名稱 HSP47 Recombinant Rabbit mAb
中文名稱 熱休克蛋白-47重組兔單抗
別    名 SERPH_HUMAN; SERPINH1; Serpin H1; 47 kDa heat shock protein; Arsenic-transactivated protein 3 (AsTP3); Cell proliferation-inducing gene 14 protein; Collagen-binding protein (Colligin); Rheumatoid arthritis-related antigen RA-A47; CBP1; CBP2; SERPINH2; PIG  
抗體來源 Rabbit
克隆類型 Recombinant
交叉反應(yīng) Human,Mouse,Rat
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46 kDa
檢測(cè)分子量 46
性    狀 Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Serpin H1 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis.

SWISS:
P50454

Gene ID:
871

信號(hào)傳導(dǎo)(Signaling Intermediates) HSP47是一類進(jìn)化上高度保守的蛋白質(zhì)家族.生理狀態(tài)時(shí)協(xié)助多肽或蛋白質(zhì)的正確轉(zhuǎn)位、折疊和裝配,起"分子伴侶"的作用;在應(yīng)激狀態(tài)下,HSP47過表達(dá)或異位表達(dá),作為一種自身抗原被免疫系統(tǒng)識(shí)別,誘發(fā)機(jī)體的保護(hù)性免疫應(yīng)答,也可作為一種信號(hào)分子,在信號(hào)轉(zhuǎn)導(dǎo)中發(fā)揮作用.
產(chǎn)品圖片
Western blot analysis of HeLa cell lysate. Using HSP47 (bsm-61347R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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