| 產(chǎn)品編號 | bsm-61409R |
| 英文名稱 | HLA G Recombinant Rabbit mAb |
| 中文名稱 | 人類白細(xì)胞抗原G重組兔單抗 |
| 別 名 | HLA G antigen; MHC class I antigen G; HLA-G; HLA60; HLAG. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38 kDa |
| 檢測分子量 | 42 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HLA G |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Non-classical major histocompatibility class Ib molecule involved in immune regulatory processes at the maternal-fetal interface. In complex with B2M/beta-2 microglobulin binds a limited repertoire of nonamer self-peptides derived from intracellular proteins including histones and ribosomal proteins. SWISS: P17693 Gene ID: 3135 人類白細(xì)胞抗原G/組織相容性白細(xì)胞抗原G(Human Leukocyte Antigen-G, HLA-G )是一種非典型的白細(xì)胞抗原Ⅰ族組織相溶性抗原。該抗原在正常情況下僅在胎盤的絨毛膜表達(dá)。在病理情況下HLA-G只在某些癌細(xì)胞表達(dá)，在正常組織或良性腫瘤則很少表達(dá).因此, HLA-G是一個(gè)具有高度腫瘤特異性的腫瘤標(biāo)志物。 近年研究認(rèn)為HLA—G作為免疫耐受分子，在腫瘤免疫逃逸中可能具有重要作用. |
| 產(chǎn)品圖片 |
Western blot analysis of Jurkat cell lysate. Using HLA G (bsm-61409R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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