| 產(chǎn)品編號(hào) | bsm-61416R |
| 英文名稱 | TERF1 Recombinant Rabbit mAb |
| 中文名稱 | 端粒體復(fù)制結(jié)合因子1重組兔單抗 |
| 別 名 | TERF1; PIN2; TRBF1; TRF1. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 16G1 |
| 交叉反應(yīng) | Human (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 50 kDa |
| 檢測(cè)分子量 | 50 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TERF1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression. SWISS: P54274 Gene ID: 7013 TRBF1端粒體復(fù)制結(jié)合因子1，在細(xì)胞周期的過程中都有該蛋白的存在，可抑制端粒酶的活性，限制染色體頂端的延長(zhǎng)。端粒體復(fù)制結(jié)合因子1位于端粒體頂端，是端粒體核酸蛋白復(fù)合物的組成部分。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with TERF1 monoclonal antibody, unconjugated (bsm-61416R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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