| 產(chǎn)品編號 | bs-6930R |
| 英文名稱 | SIK2 Rabbit pAb |
| 中文名稱 | 絲氨酸/蘇氨酸蛋白激酶SIK2抗體 |
| 別 名 | QIK; Qin induced kinase; Qin-induced kinase; Salt inducible kinase 2; Salt inducible protein kinase 2; Salt inducible serine/threonine kinase 2; Salt-inducible protein kinase 2; Serine/threonine protein kinase SIK2; Serine/threonine protein kinase SNF1 li |
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Specific References (1) | bs-6930R has been referenced in 1 publications.
[IF=2.248] Wei Shunying. et al. Overexpression of circ_CELSR1 facilitates paclitaxel resistance of ovarian cancer by regulating miR-149-5p/SIK2 axis. Anti-Cancer Drug. 2021 Jun;32(5):496-507 WB ; Human.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 104 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNF1LK2/SIK2: 281-380/926 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. Subunit: Interacts with and phosphorylates TORC2/CRTC2. Subcellular Location: Cytoplasm Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. Contains 1 protein kinase domain. Contains 1 UBA domain. SWISS: Q9H0K1 Gene ID: 23235 Database links: Entrez Gene: 23235 Human Entrez Gene: 235344 Mouse Omim: 608973 Human SwissProt: Q9H0K1 Human SwissProt: Q8CFH6 Mouse Unigene: 269128 Human Unigene: 104932 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human SH-SY5Y cell lysates
Lane 2: Human U251 cell lysates
Lane 3: Human HepG2 cell lysates
Lane 4: Human Jurkat cell lysates
Lane 5: Human A431 cell lysates
Primary: Anti-SIK2 (bs-6930R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 104 kDa
Observed band size: 100 kDa
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