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RAMP3 Rabbit pAb (bs-11972R)  
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產(chǎn)品編號 bs-11972R
英文名稱 RAMP3 Rabbit pAb
中文名稱 受體活性修飾蛋白3抗體
別    名 Calcitonin receptor like receptor activity modifying protein 3; CRLR activity modifying protein 3; CRLR activity-modifying protein 3; OTTHUMP00000159549; OTTHUMP00000214279; OTTHUMP00000214280; Receptor(calcitonin) activity modifying protein 3; Receptor(G  
Specific References  (1)     |     bs-11972R has been referenced in 1 publications.
[IF=1.86] Qiao, Xi, et al. "Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction."Nephrology (2015).  WB ;  Rat.  
研究領域 細胞生物  信號轉導  生長因子和激素  G蛋白偶聯(lián)受體  G蛋白信號  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse
產(chǎn)品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAMP3: 51-148/148 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Calcitonin receptor like receptor activity modifying protein 3; CRLR activity modifying protein 3; CRLR activity-modifying protein 3; OTTHUMP00000159549; OTTHUMP00000214279; OTTHUMP00000214280; Receptor (calcitonin) activity modifying protein 3; Receptor (G protein-coupled) activity modifying protein 3; Receptor activity modifying protein 3.

Function:
RAMP3 (receptor calcitonin activity modifying protein 3) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. It acts as a receptor for adrenomedullin (AM) together with CALCRL. It is strongly expressed in lung, breast, immune system and fetal tissues and belongs to the RAMP family.

Subunit:
Heterodimer of CALCRL and RAMP3

Subcellular Location:
Cell Membrane; Single-pass type I membrane protein

Tissue Specificity:
Strongly expressed in lung, breast, immune system and fetal tissues.

Similarity:
Belongs to the RAMP family.

SWISS:
O60896

Gene ID:
10268

Database links:

Entrez Gene: 10268 Human

Omim: 605155 Human

SwissProt: O60896 Human



產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with RAMP3 polyclonal antibody, unconjugated (bs-11972R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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