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Creatine Kinase MB Rabbit pAb (bs-14049R)  
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產(chǎn)品編號(hào) bs-14049R
英文名稱 Creatine Kinase MB Rabbit pAb
中文名稱 肌酸激酶同工酶CKMB抗體
別    名 CK-MB; B-CK; brain creatine kinase; CKBB; CKMB; CKMM; creatine kinase B; creatine kinase brain; creatine kinase M; Creatine kinase MB; Creatine Kinase MB type; creatine kinase muscle; M-CK; creatine kinase-M/B; KCRB_HUMAN; muscle creatine kinase; KCRM_HUM  
Specific References  (1)     |     bs-14049R has been referenced in 1 publications.
[IF=5.195] Chuting Li. et al. Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure. EUR J PHARMACOL. 2023 May;947:175676  WB ;  Rat.  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Sheep,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Creatine Kinase MB: 281-381/381 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

Function:
Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.

Subcellular Location:
Cytoplasmic and Mitochondrial

Similarity:
Belongs to the ATP:guanido phosphotransferase family.
Contains 1 phosphagen kinase C-terminal domain.
Contains 1 phosphagen kinase N-terminal domain.

SWISS:
P06732

Gene ID:
1158

Database links:

Entrez Gene: 1152 Human

Entrez Gene: 1158 Human

Omim: 123310 Human

SwissProt: P06732 Human

SwissProt: P12277 Human



產(chǎn)品圖片
Protein: k562(human) lysate; Primary: rabbit Anti-Creatine Kinase MB (bs-14049R) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000; Predicted band size: 42 kD Observed band size: 42 kD
Sample: Uterus (Mouse) Lysate at 40 ug Primary: Anti-Creatine Kinase MB (bs-14049R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD
Sample: Muscle (Mouse) Lysate at 40 ug Primary: Anti-Creatine Kinase MB (bs-14049R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD
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