產(chǎn)品編號(hào) | bs-16615R |
英文名稱 | Integrin beta 8 Rabbit pAb |
中文名稱 | 整合素β8抗體 |
別 名 | Integrin beta-8; ITB8_HUMAN; ITGB 8; ITGB8. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Chicken) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 81 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Integrin beta 8: 301-400/769 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] Function: Integrin alpha-V/beta-8 is a receptor for fibronectin. Subcellular Location: Membrane. Tissue Specificity: Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells. Similarity: Belongs to the integrin beta chain family. Contains 1 VWFA domain. SWISS: P26012 Gene ID: 3696 Database links: Entrez Gene: 3696 Human Entrez Gene: 320910 Mouse Entrez Gene: 100009141 Rabbit Omim: 604160 Human SwissProt: P26012 Human SwissProt: P26013 Rabbit Unigene: 592171 Human |