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KRT23 Rabbit pAb (bs-16818R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-16818R
英文名稱 KRT23 Rabbit pAb
中文名稱 細胞角蛋白23抗體
別    名 CK 23; CK-23; CK23; Cytokeratin 23; Cytokeratin-23; Cytokeratin23; DKFZP434G032; HAIK 1; HAIK1; Histone deacetylase inducible keratin 23; Hyperacetylation inducible type I keratin; K1C23_HUMAN; K23; Keratin 23(histone deacetylase inducible); Keratin 23; Keratin; Keratin type I cytoskeletal 23; Keratin-23; Keratin23; KRT 23; KRT23; MGC26158; type I cytoskeletal 23; Type I intermediate filament cytokeratin.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KRT23: 26-120/462 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function:
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane (By similarity).

Subunit:
Interacts with ERLEC1 (By similarity).

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).

Similarity:
Contains 1 CUB domain.
Contains 1 kringle domain.
Contains 1 WSC domain.

SWISS:
Q9C075

Gene ID:
25984

Database links:

Entrez Gene: 25984 Human

Omim: 606194 Human

SwissProt: Q9C075 Human

Unigene: 9029 Human



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