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SLC19A2 Rabbit pAb (bs-10738R)  
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50ul/1180.00元
100ul/1980.00元
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產品編號 bs-10738R
英文名稱 SLC19A2 Rabbit pAb
中文名稱 SLC19A2抗體
別    名 Thiamine transporter 1; S19A2_HUMAN; SLC19A2; Solute carrier family 19 member 2; TC1; Thiamine carrier 1; THT1; ThTr 1; ThTr-1; ThTr1; TRMA.  
研究領域 腫瘤  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC19A2: 21-120/497 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. [provided by RefSeq, Jul 2008]

Function:
High-affinity transporter for the intake of thiamine.

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung.

DISEASE:
Defects in SLC19A2 are the cause of thiamine-responsive megaloblastic anemia syndrome (TRMA) [MIM:249270]; also known as Rogers syndrome. TRMA is an autosomal recessive disease with features that include megaloblastic anemia, mild thrombocytopenia and leucopenia, sensorineural deafness and diabetes mellitus.

Similarity:
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

SWISS:
O60779

Gene ID:
10560

Database links:

Entrez Gene: 10560 Human

Entrez Gene: 116914 Mouse

Entrez Gene: 289175 Rat

Omim: 603941 Human

SwissProt: O60779 Human

SwissProt: Q9EQN9 Mouse

SwissProt: Q499Q0 Rat

Unigene: 30246 Human



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