產(chǎn)品編號 | bs-17049R |
英文名稱 | KIF22 Rabbit pAb |
中文名稱 | 驅(qū)動蛋白家族成員22抗體 |
別 名 | A 328A3.2; KID; KIF 22; kif22; KIF22_HUMAN; Kinesin family member 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA binding protein pseudogene; Kinesin like protein 4; Kinesin like protein KIF22; Kinesin-like DNA-binding protein; Kinesin-like protein 4; Kinesin-like protein KIF22; KNSL 4; KNSL4; OBP 1; OBP 2; OBP; OBP1; OBP2; Origin of plasmid DNA replication binding protein; OriP binding protein; OTTHUMP00000123406. |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Zebrafish,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 73 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KIF22: 221-320/665 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Subcellular Location: Nucleus. Cytoplasm; cytoskeleton. Post-translational modifications: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. SWISS: Q14807 Gene ID: 3835 Database links: Entrez Gene: 3835 Human Entrez Gene: 110033 Mouse Omim: 603213 Human SwissProt: Q14807 Human SwissProt: Q3V300 Mouse Unigene: 612151 Human Unigene: 286488 Mouse Unigene: 8601 Rat |