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LARP4B/LARP5 Rabbit pAb (bs-17104R)  
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產(chǎn)品編號(hào) bs-17104R
英文名稱 LARP4B/LARP5 Rabbit pAb
中文名稱 LARP4B蛋白抗體
別    名 A630096F19; AI256361; D13Wsu64e; KIAA0217; La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La-related protein 4B; La-related protein 5; LAR4B_HUMAN; Larp4b; LARP5; MGC78318.  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse (predicted: Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 81 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LARP4B/LARP5: 401-500/738 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012]

Function:
Stimulates mRNA translation.

Subunit:
Interacts with PABPC1 and GNB2L1. Associates with polysomes via the 40S ribosomal subunit.

Subcellular Location:
Cytoplasm, cytosol

Similarity:
Contains 1 HTH La-type RNA-binding domain.
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q92615

Gene ID:
23185

Database links:

Entrez Gene: 23185 Human

SwissProt: Q92615 Human

Unigene: 631814 Human



產(chǎn)品圖片
Sample: 293T(Human) Cell Lysate at 30 ug Primary: Anti-LARP5 (bs-17104R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 81 kD Observed band size: 81 kD
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LARP4B) Polyclonal Antibody, Unconjugated (bs-17104R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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