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LY6G6F Rabbit pAb (bs-20073R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-20073R
英文名稱 LY6G6F Rabbit pAb
中文名稱 淋巴細胞抗原6重復位點蛋白G6F抗體
別    名 C6orf21; Chromosome 6 open reading frame 21; G6F; G6f protein [Precursor]; HCG43720, isoform CRA_c; LY66F_HUMAN; LY6G6D; Ly6g6f; Lymphocyte antigen 6 complex locus G6F; Lymphocyte antigen 6 complex locus protein G6f; Lymphocyte antigen 6 complex, locus G6D; NG32.  
Specific References  (2)     |     bs-20073R has been referenced in 2 publications.
[IF=9.473] Li-Wei Liu. et al. Gut microbiota-derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling. BRIT J PHARMACOL. 2022 Nov;:  IHC ;  Rat, Mouse.  
[IF=6.832] Zhang, Yaqi. et al. MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization. STEM CELL RES THER. 2022 Dec;13(1):1-16  IHC ;  Rat.  
研究領域 細胞生物  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat LY6G6F: 101-200/293 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 lymphocyte antigen 6 complex locus protein G6f is a single-pass type I membrane protein belonging to the immunoglobulin (Ig) superfamily. Located in the class III region of the major histocompatibility complex (MHC), the G6f gene lies in a cluster of genes encoding cell-surface proteins that play a role in the immune system and cellular recognition. G6f functions as a downstream effector of GRB2 and GRB7, and, in humans, it interacts with GRB2 and GRB7 through the phosphorylation of a tyrosine residue (Tyr 281) in the intracellular tail of G6f. This interaction is also mediated by the SH2 domain of GRB2 and possibly that of GRB7. G6f is a 297 amino acid protein, and it forms a disulfide-linked homodimer.

Function:
May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.

Subcellular Location:
Cell membrane.

Post-translational modifications:
modificationsN-glycosylated.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
Q6MG56

Gene ID:
309609

Database links:

Entrez Gene: 259215 Human

Entrez Gene: 309609 Rat

Entrez Gene: 433099 Mouse

Omim: 611404 Human

SwissProt: Q5SQ64 Human

SwissProt: Q7Z5H2 Human

SwissProt: Q6MG56 Rat

Unigene: 591794 Human

Unigene: 145028 Rat



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