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FABP4 Mouse mAb (bsm-51247M)  
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產品編號 bsm-51247M
英文名稱 FABP4 Mouse mAb
中文名稱 脂肪細胞型脂肪酸結合蛋白單克隆抗體
別    名 adipocyte; 3T3-L1 lipid-binding protein; 422/aP2; A FABP; A-FABP; Adipocyte lipid binding protein; Adipocyte lipid-binding protein; Adipocyte protein AP2; Adipocyte-type fatty acid-binding protein; AFABP; ALBPv ALBP/Ap2; aP2; FABP; FABP4_HUMAN; Fatty acid  
Specific References  (5)     |     bsm-51247M has been referenced in 5 publications.
[IF=7.012] Mengqi Su. et al. Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner. TRANSL RES. 2022 May;:  FC ;  Mouse.  
[IF=5.923] Yonglin Hua. et al. Ablation of KDM2A Inhibits Preadipocyte Proliferation and Promotes Adipogenic Differentiation. Int J Mol Sci. 2021 Jan;22(18):9759  IF ;  Mouse.  
[IF=5.201] Xuemei Shen. et al. CircINSR Regulates Fetal Bovine Muscle and Fat Development. Front Cell Dev Biol. 2020; 8: 615638  WB ;  Bovine.  
[IF=4.861] Xuemei Shen. et al. CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p. EPIGENETICS-US. 2022 Nov 15  WB ;  Bovine.  
[IF=1.966] Zhang Y et al. High expression of FABP4 and FABP6 in patients with colorectal cancer. World J Surg Oncol. 2019 Oct 24;17(1):171.  IHC-P&WB ;  Human.  
研究領域 腫瘤  免疫學  轉錄調節(jié)因子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 6F3
交叉反應 Mouse (predicted: Human)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:20-200,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human FABP4 protein 
亞    型
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq].

Function:
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.

Subunit:
Monomer. Homodimer. Interacts with PPARG.

Subcellular Location:
Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

SWISS:
P15090

Gene ID:
2167

Database links:

Entrez Gene: 2167 Human

Entrez Gene: 11770 Mouse

Entrez Gene: 79451 Rat

Omim: 600434 Human

SwissProt: P15090 Human

SwissProt: P04117 Mouse

SwissProt: P70623 Rat

Unigene: 391561 Human

Unigene: 582 Mouse

Unigene: 4258 Rat



產品圖片
Sample: Lane 1: Mouse Adipose tissue lysates Lane 2: Mouse Breast tissue lysates Lane 3: Mouse Heart tissue lysates Lane 4: Mouse Thymus tissue lysates Primary: Anti-FABP4 (bsm-51247M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 14 kDa
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