| 產品編號 | bsm-52427R |
| 英文名稱 | CAMK2 beta Recombinant Rabbit mAb |
| 中文名稱 | 鈣/鈣調素依賴蛋白激酶CAMK2B重組兔單克隆抗體 |
| 別 名 | Calcium/calmodulin dependent protein kinase(CaM kinase) II beta; Calcium/calmodulin dependent protein kinase II beta; Calcium/calmodulin dependent protein kinase IIB; Calcium/calmodulin dependent protein kinase type II beta chain; calcium/calmodulin-depen |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 1H12 |
| 交叉反應 | (predicted: Human,Mouse,Rat) |
| 產品應用 | WB=1:500-1000,IHC-P=1:50-100,IHC-F=1:50-100,IF=1:50-100
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 61 kDa |
| 檢測分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Human CaMKII between 200-300 amino acids |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CaMKII is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory. SWISS: Q13554 Gene ID: 816 CaMK2b也是絲/蘇氨基酸激酶的一種，有稱CAMK2G，同屬于Ca++/鈣調素依賴性蛋白質激酶家族成員。鈣／鈣調素依賴性蛋白激酶Ⅱb（CaMKⅡb）廣泛分布于中樞神經系統(tǒng)內，參與調節(jié)神經遞質的合成釋放、信號轉導和突觸可塑性的形成以及磷酸化蛋白。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
