| 產(chǎn)品編號 | D60173 |
| 英文名稱 | Trimipramine Maleate Salt |
| 中文名稱 | 三甲丙咪嗪馬來酸鹽 |
| 別 名 | Surmontil maleate |
| 克 隆 號 | |
| CAS | 521-78-8 |
| 理論分子量 | 410.51 kDa |
| 檢測分子量 | |
| 保存條件 | 2-8℃ |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Trimipramine maleate is a 5-HT receptor antagonist, with pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively. Trimipramine maleate is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 μM, 2.11 μM, 3.72 μM, 8.00 μM, respectively. Trimipramine maleate has vascular activity and anxiolytic efficacy |
