產品編號 | bs-1279R-Cy3 |
英文名稱 | Rabbit Anti-HLA E/Cy3 Conjugated antibody |
中文名稱 | Cy3標記的人類白細胞抗原E抗體 |
別 名 | HLA class I histocompatibility antigen E alpha chain; DKFZp686P19218; EA1.2; EA2.1; HLA 6.2; HLA class I histocompatibility antigen alpha chain E; HLA class I histocompatibility antigen E alpha chain precursor; HLA-6.2; HLA6.2; HLAE; Lymphocyte antigen; Major histocompatibility complex class I E; MHC; MHC class I antigen E; MHC HLA E alpha 1; MHC HLA E alpha 2.1;HLA-E; QA1. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 腫瘤 免疫學 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Human, |
產品應用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 37kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HLA E |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008] Function: Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules. Subunit: Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain. Database links: Entrez Gene: 3133 Human Omim: 143010 Human SwissProt: P13747 Human Unigene: 650174 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 人類白細胞抗原E(Human Leukocyte Antigen-E )是一種非典型的白細胞抗原Ⅰ族組織相溶性抗原,在病理情況下HLA-G只在某些癌細胞表達,HLA-E是一個具有高度腫瘤特異性的腫瘤標志物。 |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |