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Rabbit Anti-KRT28/BF555 Conjugated antibody (bs-16822R-BF555)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-16822R-BF555
英文名稱(chēng) Rabbit Anti-KRT28/BF555 Conjugated antibody
中文名稱(chēng) BF555標(biāo)記的細(xì)胞角蛋白28抗體
別    名 CK-28; Cytokeratin-28; K1C28_HUMAN; K25D; K28; Keratin 25D; Keratin 28; Keratin; Keratin, type I cytoskeletal 28; Keratin-25D; Keratin-28; KRT25D; KRT28; type I cytoskeletal 28; Type I inner root sheath specific keratin 25 irs4; Type I inner root sheath-specific keratin-K25irs4.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KRT28
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]

Function:
Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs).

Subunit:
Heterotetramer of two type I and two type II keratins.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Strongly expressed in skin and scalp, and weak expression observed in thymus. In the hair follicle, expressed in Henle layer, Huxley layer and in the irs cuticle. Expression extends from the bulb region up to the point of differentiation into the three layers. Also present in the medulla of beard hair (at protein level).

Similarity:
Belongs to the intermediate filament family.

Database links:

Entrez Gene: 788909 Cow

Entrez Gene: 162605 Human

Entrez Gene: 70843 Mouse

SwissProt: Q148H6 Cow

SwissProt: Q7Z3Y7 Human

SwissProt: A6BLY7 Mouse

Unigene: 59736 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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