| 產(chǎn)品編號 | bs-16830R-AP |
| 英文名稱 | Rabbit Anti-KRT71/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的細(xì)胞角蛋白71抗體 |
| 別 名 | CK-71; Cytokeratin-71; hK6irs; hK6irs1; K2C71_HUMAN; K6IRS1; K71; Keratin 6 irs; Keratin; keratin, type II cytoskeletal 71; Keratin-71; KRT6IRS; KRT6IRS1; KRT71; MGC119390; MGC119391; OTTHUMP00000236990; type II cytoskeletal 71; Type II inner root sheath-specific keratin-K6irs1; Type-II keratin Kb34. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 57kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KRT71 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009] Function: Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. Subunit: Heterodimer of a type I and a type II keratin. Associates with KRT16 and/or KRT17 (By similarity). Tissue Specificity: Highly expressed in hair follicles from scalp. Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in the all 3 IRS layers: the cuticle, the Henle and the Huxley layers. Also detected in the pseudopods of specialized Huxley cells, termed Fluegelzellen, along the area of differentiated Henle cells (at protein level). DISEASE: Hypotrichosis 13 (HYPT13) [MIM:615896]: A form of hypotrichosis, a condition characterized by the presence of less than the normal amount of hair and abnormal hair follicles and shafts, which are thin and atrophic. The extent of scalp and bodyhair involvement can be very variable, within as well as between families. HYPT13 is characterized by sparse woolly hair. Similarity: Belongs to the intermediate filament family. Database links: Entrez Gene: 112802 Human Omim: 608245 Human SwissProt: Q3SY84 Human Unigene: 660007 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
