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Rabbit Anti-KAP3.3/Gold Conjugated antibody (bs-16851R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-16851R-Gold
英文名稱 Rabbit Anti-KAP3.3/Gold Conjugated antibody
中文名稱 膠體金標記的角蛋白相關蛋白KAP3.3抗體
別    名 KRTAP3-3 High sulfur keratin-associated protein 3.3; KAP3.3; Keratin-associated protein 3-3; Keratin-associated protein 3.3; KRA33_HUMAN; Krtap3-3; KRTAP3.3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KAP3.3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Tissue Specificity:
Localized to the upper cortex of the hair shaft.

Similarity:
Belongs to the KRTAP type 3 family.

Database links:

Entrez Gene: 768045 Cow

Entrez Gene: 85293 Human

Entrez Gene: 66380 Mouse

Entrez Gene: 363678 Rat

SwissProt: Q24JX9 Cow

SwissProt: Q9BYR6 Human

SwissProt: Q9D7P0 Mouse

Unigene: 662759 Human

Unigene: 30539 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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