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Rabbit Anti-KIF18A/HRP Conjugated antibody (bs-17042R-HRP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17042R-HRP
英文名稱 Rabbit Anti-KIF18A/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的驅(qū)動蛋白家族成員18A抗體
別    名 AU024633; B130001M12Rik; DKFZp434G2226; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; MS-KIF18A; RGD1561740; RP23 206C1.1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 102kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF18A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
KIF18A is a 898 amino acid protein that contains one kinesin-motor domain, which is responsible for the ATP-dependent movement of KIF18A across microtubules. KIF18A plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. Expression of KIF18A is induced by estrogen.

Function:
Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.

Subcellular Location:
Cell projection > ruffle. Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.

Post-translational modifications:
Glycosylated.
Ubiquitinated.

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.

Database links:

Entrez Gene: 81930 Human

Omim: 611271 Human

SwissProt: Q8NI77 Human

Unigene: 301052 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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